Experimental molecules fight covid
Two MIT research groups have designed biological molecules that could help combat the effects of covid-19.
One team, led by principal research scientist Shuguang Zhang and research scientist Rui Qing, developed proteins that could be injected into the body to block “cytokine storms,” immune-system overreactions that damage the lungs and can be fatal. The proteins, lab-modified versions of naturally occurring cytokine receptors, could bind to excess cytokines and remove them from the system, says Qing. Tests in human cells and animal models are planned.
The other team, led by associate professor of chemistry Brad Pentelute, designed a short protein fragment, or peptide, that can bind to the viral protein used to enter human lung cells, potentially disarming it. The peptide mimics a cell surface protein that attaches to one of the protein spikes protruding from the coronavirus. The researchers have sent samples to collaborators who plan to carry out tests in human cells.
Keep Reading
Most Popular
How scientists traced a mysterious covid case back to six toilets
When wastewater surveillance turns into a hunt for a single infected individual, the ethics get tricky.
The problem with plug-in hybrids? Their drivers.
Plug-in hybrids are often sold as a transition to EVs, but new data from Europe shows we’re still underestimating the emissions they produce.
What’s next for generative video
OpenAI's Sora has raised the bar for AI moviemaking. Here are four things to bear in mind as we wrap our heads around what's coming.
Stay connected
Get the latest updates from
MIT Technology Review
Discover special offers, top stories, upcoming events, and more.