Experimental molecules fight covid
Two MIT research groups have designed biological molecules that could help combat the effects of covid-19.
One team, led by principal research scientist Shuguang Zhang and research scientist Rui Qing, developed proteins that could be injected into the body to block “cytokine storms,” immune-system overreactions that damage the lungs and can be fatal. The proteins, lab-modified versions of naturally occurring cytokine receptors, could bind to excess cytokines and remove them from the system, says Qing. Tests in human cells and animal models are planned.
The other team, led by associate professor of chemistry Brad Pentelute, designed a short protein fragment, or peptide, that can bind to the viral protein used to enter human lung cells, potentially disarming it. The peptide mimics a cell surface protein that attaches to one of the protein spikes protruding from the coronavirus. The researchers have sent samples to collaborators who plan to carry out tests in human cells.
Keep Reading
Most Popular

Why China is still obsessed with disinfecting everything
Most public health bodies dealing with covid have long since moved on from the idea of surface transmission. China’s didn’t—and that helps it control the narrative about the disease’s origins and danger.

These materials were meant to revolutionize the solar industry. Why hasn’t it happened?
Perovskites are promising, but real-world conditions have held them back.

Crypto is weathering a bitter storm. Some still hold on for dear life.
When a cryptocurrency’s value is theoretical, what happens if people quit believing?

Anti-aging drugs are being tested as a way to treat covid
Drugs that rejuvenate our immune systems and make us biologically younger could help protect us from the disease’s worst effects.
Stay connected

Get the latest updates from
MIT Technology Review
Discover special offers, top stories, upcoming events, and more.