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MIT Technology Review

Making Eyes

Over roughly nine days, a ball of mouse embryonic stem cells (gray) gives rise to a cup-shaped structure (green) with a complex three-dimensional architecture identical to the retina in early development. A tiny sac of cells balloons outward from the clump’s surface; then the sac folds in on itself, with retinal pigment cells on the outside and retinal neurons on the inside.

Over roughly nine days, a ball of mouse embryonic stem cells (gray) gives rise to a cup-shaped structure (green) with a complex three-dimensional architecture identical to the retina in early development. A tiny sac of cells balloons outward from the clump’s surface; then the sac folds in on itself, with retinal pigment cells on the outside and retinal neurons on the inside.