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Entrepreneurs

Jon Han

35 Innovators Under 35

Entrepreneurs

Meet the people who are taking innovations like CRISPR and flexible electronics and turning them into businesses.

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Rachel Haurwitz, 32

Caribou Biosciences

Overseeing the commercialization of the promising gene-editing method called CRISPR.

Rachel Haurwitz quickly went from lab rat to CEO at the center of the frenzy over CRISPR, the breakthrough gene-editing technology. In 2012 she’d been working at Jennifer Doudna’s lab at the University of California, Berkeley, when it made a breakthrough showing how to edit any DNA strand using CRISPR. Weeks later, Haurwitz traded the lab’s top-floor views of San Francisco Bay for a sub-basement office with no cell coverage and one desk. There she became CEO of Caribou Biosciences, a spinout that has licensed Berkeley’s CRISPR patents and has made deals with drug makers, research firms, and agricultural giants like DuPont. She now oversees a staff of 44 that spends its time improving the core gene-editing technology. One recent development: a tool called SITE-Seq to help spot when CRISPR makes mistakes.

—Antonio Regalado