The Wellcome Trust announced the winners of its
annual Wellcome Image
Awards last night in London, highlighting 19 stunning images that reveal
nature’s often hidden beauty.
We describe a few tech-worthy selections from the
list below. For the full slideshow–along with information on how the images were made
and why they were selected–click here.
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Synthetic polymers used to coat a drug, which are used to slow release of a drug or to target it to part of the digestive tract.
Of the image above, the Wellcome Image site says:
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Polymers play an important role in reducing
side-effects of drugs, as well as the number of times a patient needs to take a
medication. Scanning electron micrograph images are taken in black and white
and are colored later. The orange spheres contain the drug and the
encapsulating co-polymers are coloured blue.
Judge Catherine Draycott says this image was picked
because “it doesn’t look like a natural image. It doesn’t look as
though it could possibly come from a microscope – it looks as though it
must be computer-generated…The image really shows what technology can do in
targeting drugs to specific purposes. This system is designed to delay the
release of the drug that is contained in the smaller particles until it reaches
the large intestine, where it will treat inflammatory bowel disease.”
A three-dimensional reconstruction of an embryonic mouse head, age 14.5 days.
This image above was created using high-resolution episcopic microscopy. The Welcome site says:
Samples are embedded in plastic stained with a fluorescent dye. Each time a fine section of the sample is sliced away, an image of the remaining sample is captured. These images are then put together to create a 3D animation of the external and internal structure of the sample.
Of the mouse image, Judge Gonzalo Blanco says “from the point of view of
developmental biology, this new tool can illustrate much more effectively the
impact that certain mutations may have on the anatomy of the mouse embryo.
Usually you can only see a section, but by exposing the same reconstruction
through different filters, you can actually see in 3D view – from many angles –
the developmental defect.”
Capillaries that connect arteries and veins.
The last image was captured from a slide prepared in the 1980s and acquired from a retired histologist.
According to the Wellcome Image site:
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The cillary body in an ox’s eye has been dissected away from the lens and laid
onto the slide. The bright red colour of the capillaries is visible owing to a
dye – likely to be carmine dye – which was injected into the artery that
supplied the capillaries. Due to the thickness of the sample, this image was
created from a stack of images that were combined to give the structure a 3D
appearance.
