This is something you haven’t seen before: an image of a live, quarter-millimeter-long C. elegans worm whose internal organs, tail, and pharynx are clearly visible. The image was made by a microscope, under development at MIT, that renders cells and tiny organisms in 3‑D detail by exploiting the ways that different cell structures refract light and combining images made from several angles. In conventional microscopy, the cell or organism being studied must be treated with fixing agents and stains. “Our technique allows you to study cells in their native state with no preparation at all,” says Michael Feld, a professor of physics at MIT, who led the microscope’s development. In addition to imaging the worm, his group has imaged cervical-cancer cells, which could be seen shriveling up when treated with acetic acid. Because it can show how cells react to different compounds, the technology could be useful in drug screening.
Toronto wants to kill the smart city forever
The city wants to get right what Sidewalk Labs got so wrong.
Saudi Arabia plans to spend $1 billion a year discovering treatments to slow aging
The oil kingdom fears that its population is aging at an accelerated rate and hopes to test drugs to reverse the problem. First up might be the diabetes drug metformin.
Yann LeCun has a bold new vision for the future of AI
One of the godfathers of deep learning pulls together old ideas to sketch out a fresh path for AI, but raises as many questions as he answers.
The dark secret behind those cute AI-generated animal images
Google Brain has revealed its own image-making AI, called Imagen. But don't expect to see anything that isn't wholesome.
Get the latest updates from
MIT Technology Review
Discover special offers, top stories, upcoming events, and more.