Mastering Memory


The search for drugs to treat Alzheimer’s and other dementias has been slow and difficult. But recent research has shown that epigenetic processes—heritable changes that do not alter the sequence of DNA—play a huge role in memory and brain development. In mouse studies, drugs directed at such processes have enhanced animals’ short- and long-term memory and even allowed them to recall lost memories. Scientists plan to begin testing some drugs in humans within a year, and the hunt for new drugs continues. Emily Singer, Technology Review Michael Ahlijanian, EnVivo Pharmaceuticals Karim Nader, McGill University Joe Tsien, Medical School of Georgia.

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May 8, 2017

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