Skip to Content
Biotechnology and health

The first women in the UK will undergo a radical ‘three-person’ IVF technique

February 2, 2018

Doctors will use a cutting-edge IVF technique to help two couples have healthy babies.

The news: British regulators have approved the first uses of a technique called mitochondrial replacement therapy in the UK. The approach will use DNA from three people—the parents and a female donor—to avoid passing on a devastating neurodegenerative disorder caused by faulty mitochondria.

How it works: Doctors fertilize a woman’s egg with sperm and remove its nucleus, leaving the defective mitochondrial DNA behind. They then inject the nucleus into a hollowed-out donor egg containing only healthy mitochondrial DNA.

US opposition: It’s unlikely the US will follow Britain’s lead anytime soon. Congress has effectively barred research that involves implanting modified embryos in a person. New York fertility doctor John Zhang had to go to Mexico to perform a similar procedure, which resulted in the birth of a seemingly healthy baby boy in 2016.

Deep Dive

Biotechnology and health

How scientists traced a mysterious covid case back to six toilets

When wastewater surveillance turns into a hunt for a single infected individual, the ethics get tricky.

An AI-driven “factory of drugs” claims to have hit a big milestone

Insilico is part of a wave of companies betting on AI as the "next amazing revolution" in biology

The quest to legitimize longevity medicine

Longevity clinics offer a mix of services that largely cater to the wealthy. Now there’s a push to establish their work as a credible medical field.

There is a new most expensive drug in the world. Price tag: $4.25 million

But will the latest gene therapy suffer the curse of the costliest drug?

Stay connected

Illustration by Rose Wong

Get the latest updates from
MIT Technology Review

Discover special offers, top stories, upcoming events, and more.

Thank you for submitting your email!

Explore more newsletters

It looks like something went wrong.

We’re having trouble saving your preferences. Try refreshing this page and updating them one more time. If you continue to get this message, reach out to us at customer-service@technologyreview.com with a list of newsletters you’d like to receive.