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Sustainable Energy

Transforming Adult Cells into Stem Cells

Mimicking human disease in a dish.

Slideshow: James Thomson and Junying Yu (above) first transformed adult cells into stem cells called iPS cells in 2007.
Slideshow: Yu, now at Cellular Dynamics, is developing more efficient ways of making the cells, which are the starting ingredient used to make cardiac muscle cells.
Slideshow: A precise combination of chemicals, agitation, and temperature transforms the iPS cells into heart cells (above), which fall to the bottom of the flask when it stops moving (next image).
Slideshow: iPS cells are transformed into heart cells and fall to the bottom of the flask when it stops moving.
Slideshow: Colonies of heart cells beat in sync when grown on a dish.
Slideshow: Five weeks after iPS cells have been thawed, vials of muscle cells are ready to be shipped to customers.

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