Hello,

We noticed you're browsing in private or incognito mode.

To continue reading this article, please exit incognito mode or log in.

Not an Insider? Subscribe now for unlimited access to online articles.

Katherine Bourzac

A View from Katherine Bourzac

First Complete Image of a Molecule, Atom by Atom

Researchers at IBM have used an atomic-force microscope to resolve the chemical structure of pentacene.

  • August 27, 2009

Using an atomic-force microscope, scientists at IBM Research in Zurich have for the first time made an atomic-scale resolution image of a single molecule, the hydrocarbon pentacene.

This image of pentacene, a molecule
made up of five carbon rings, was
made using an atomic-force
microscope. Credit: Science/AAAS

Atomic-force microscopy works by scanning a surface with a tiny cantilever whose tip comes to a sharp nanoscale point. As it scans, the cantilever bounces up and down, and data from these movements is compiled to generate a picture of that surface. These microscopes can be used to “see” features much smaller than those visible under light microscopes, whose resolution is limited by the properties of light itself. Atomic-force microscopy literally has atom-scale resolution.

Still, until now, it hasn’t been possible to use it to look with atomic resolution at single molecules. On such a scale, the electrical properties of the molecule under investigation normally interfere with the activity of the scanning tip. Researchers at IBM Research in Zurich overcame this problem by first using the microscope tip to pick up a single molecule of carbon monoxide. This drastically improved the resolution of the microscope, which the IBM scientists used to make an image of pentacene. They arrived at carbon monoxide as a contrast-enhancing addition after trying many chemicals.

The researchers hope that looking this closely at single molecules will give them a better understanding of chemical reactions and catalysis at an unprecedented level of detail.

The imaging work is described today in the journal Science.

Be the leader your company needs. Implement ethical AI.
Join us at EmTech Digital 2019.

Register now
Want more award-winning journalism? Subscribe to Insider Basic.
  • Insider Basic {! insider.prices.basic !}*

    {! insider.display.menuOptionsLabel !}

    Six issues of our award winning print magazine, unlimited online access plus The Download with the top tech stories delivered daily to your inbox.

    See details+

    Print Magazine (6 bi-monthly issues)

    Unlimited online access including all articles, multimedia, and more

    The Download newsletter with top tech stories delivered daily to your inbox

/3
You've read of three free articles this month. for unlimited online access. You've read of three free articles this month. for unlimited online access. This is your last free article this month. for unlimited online access. You've read all your free articles this month. for unlimited online access. You've read of three free articles this month. for more, or for unlimited online access. for two more free articles, or for unlimited online access.