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Biomedicine

How Heart-Muscle Devices Are Made

Devices made of heart tissue could screen drug candidates and be used to power implantable robots.

Feinberg uses a pipette to apply a protein called fibronectin to a clear polymer stamp patterned with microscopic lines.
He presses the stamp onto a silicone­-coated coverslip, transferring lines of the protein to the silicone.
Then he immerses the coverslip in a solution of heart cells (red liquid). The protein lines direct the growth of heart tissue.
Adam Feinberg has made a simple heart-muscle-powered actuator: a strip of polymer that flexes when the muscle contracts.
Through a low-powered microscope, the orientation of the muscle tissue is visible near the point where he grips the elastic film with a pair of forceps.
Feinberg controls the rate of the contractions by changing the frequency of electronic pulses.
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