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MIT Technology Review
  • 1

    Why

    While advancing autopilot technology in its Model S and X cars, the company is taking electric vehicles mainstream with its $35,000 Model 3 car, which already has 400,000 pre-orders.

    50 percent

    According to CEO Elon Musk, drivers have a 50 percent lower chance of having an accident when driving with Tesla Autopilot.

    Company Details
  • 2

    Why

    $45 billion

    Most recent valuation for the private company

    Company Details
  • 3

    Why

    After a drop in sales last fall, unveiled a new machine, NovaSeq, that will be capable of sequencing 48 entire human genomes in two and a half days—and could one day push the cost of genome sequencing down to $100.

    $850,000:

    price of the cheaper of its two NovaSeq models

    Company Details
  • 4

    Why

    Quickly expanding the artificial intelligence in its Alibaba Cloud platform, including industry-specific products, and launching a global electronic trade platform to build its business with small and medium-size companies around the world.

    57 percent:

    Alibaba’s share of Chinese online commerce

    Company Details
  • 5

    Why

    3.6 percent

    Proportion of U.S. couples that use its tests before trying to conceive

    Company Details
  • 6

    Why

    1.1 billion

    number of people worldwide who don’t have access to electricity

    Company Details
  • 7

    Why

    Turning its insanely popular chat platform WeChat into a virtual operating system featuring mini programs.

    50 percent:

    proportion of WeChat’s 770 million daily users who are on the service at least 90 minutes a day

    Company Details
  • 8

    Why

    $304 million

    Amount it raised in the largest biotech IPO of 2014

    Company Details
  • 9

    Why

    177,000

    Number of U.S. customers who lease SolarCity’s rooftop solar panels

    Company Details
  • 10

    Why

    31

    Number of Emmy nominations for its original programming in 2014

    Company Details
  • 11

    Why

    $25,000

    Maximum amount it charges IVF clinics for the treatment

    Company Details
  • 12
  • 13

    Why

    Creating an AI-powered store of the future with Amazon Go while expanding intelligent voice assistant Alexa into phones, cars, and more.

    12,000:

    number of programs that software developers have published for Alexa

    Company Details
  • 14

    Why

    2 million

    Number of ECG readings on its devices so far

    Company Details
  • 15

    Why

    $3.6 billion


    Sales of the drug in the first three months of 2015

    Company Details
  • 16

    Why

    Minting money selling its popular mobile phones and laptops while adding impressive names to its AI research team and promising to do more manufacturing in the U.S.

    $257 billion:

    cash on its balance sheet, more than the entire market value of General Electric

    Company Details
  • 17

    Why

    5,000

    Factor by which its inks improve conductivity, according to the company

    Company Details
  • 18

    Why

    Its large-scale desalination process is winning big contracts in China and Australia.

    30 percent

    By October IDE will be producing 30 percent of Santa Barbara’s water.

    Company Details
  • 19

    Why

    10,000

    Number of sequenced genomes in the database

    Company Details
  • 20

    Why

    Its innovative batteries for the power grid make this startup unusually successful in a tough industry.

    Backers

    Include Bill Gates, Shell.

    Company Details
  • 21

    Why

    Despite the high-profile loss this year of its well-regarded head of AI, Andrew Ng, the company is doing important work in the field, including leading China’s National Engineering Lab of Deep Learning Technology and Application.

    1,300:

    number of employees dedicated to working on AI

    Company Details
  • 22

    Why

    Changing the economics of space travel with its successful landing and recycling of rockets to be recycled for multiple trips

    10 percent:

    price discount being considered for customers who agree to fly their payloads on reused rockets

    Company Details
  • 23

    Why

    $15 million

    Size of recent investment by appliance maker Dyson (General Motors is also a backer)

    Company Details
  • 24

    Why

    $12 billion

    Freescale’s value in a proposed acquisition by a Dutch semiconductor maker

    Company Details
  • 25

    Why

    70 percent

    Increase in revenue from 2013 to 2014

    Company Details
  • 26

    Why

    Uses of its life-saving immunotherapy, Opdivo, has expanded to lung cancer, advanced renal-cell carcinoma, and Hodgkin’s lymphoma.

    Five years

    One-third of patients with advanced melanoma survived for five years in a study of Opdivo.

    Company Details
  • 27

    Why

    10 million

    Number of U.S. members in its remote-consultation service

    Company Details
  • 28

    Why

    Continues to tweak its chips, originally developed for gaming, to help develop breakthrough technologies like deep learning and autonomous driving.

    $3 billion:

    spending on R&D to create its new data-center chip

    Company Details
  • 29

    Why

    Despite controversies over fake news, live streaming video, and discriminatory advertising, and poor sales of its Oculus VR headset, it continues to work on interesting applications of AI and VR, and its Instagram business is singing.

    20:

    number of natural-language data sets built into the company’s AI research tool, ParlAI.

    Company Details
  • 30

    Why

    6

    Number of the company’s drugs in human testing

    Company Details
  • 31

    Why

    $114 million

    Funding raised

    Company Details
  • 32

    Why

    $5

    Retail price of two bulbs that will last for a decade

    Company Details
  • 33

    Why

    Last summer a hospital in London used Cellectis’s gene-editing technology to heal a child with otherwise untreatable leukemia.

    $300 million

    Though not profitable, the company has over $300 million in cash, enough to last through 2018.

    Company Details
  • 34

    Why

    Leading gene-therapy company focuses on engineered T cells that recognize and kill cancer and other conditions. Its treatment for sickle-cell disease appears promising.

    66 percent:

    increase in stock price over the past year

    Company Details
  • 35

    Why

    6.4 billion euros

    Company’s global elevator sales in 2014

    Company Details
  • 36

    Why

    The workplace communications app burrows more deeply into workplaces. Now you can use your Slack login for all the software your company uses.

    Three million

    Number of daily active Slack users.

    Company Details
  • 37

    Why

    205 million

    Number of monthly active users

    Company Details
  • 38

    Why

    Its virtual-world simulation platform is used to create VR software and test driverless cars.

    Funding

    Andreessen Horowitz is a major backer.

    Company Details
  • 39

    Why

    A number of Australian radiologists are now using the company’s deep-learning software to analyze x-rays.

    50 percent

    Claims its algorithm read chest CT images 50 percent more accurately than experts in its own test.

    Company Details
  • 40

    Why

    2.9 million

    Number of Bitcoin accounts registered with Coinbase

    Company Details
  • 41

    Why

    40 million

    Number of journeys planned on its system every day

    Company Details
  • 42

    Why

    50

    Factor by which 3D Systems hopes to increase the speed of 3-D printing

    Company Details
  • 43

    Why

    60

    Number of countries in which the company operates

    Company Details
  • 44

    Why

    The Oxitec division of this biotech holding company genetically engineers mosquitoes that could reduce the spread of Zika.

    $174 million

    Acquisitions increased sales from $8 million to $174 million in five years.

    Company Details
  • 45

    Why

    56,000

    Number of computer processors the company uses to analyze DNA

    Company Details
  • 46

    Why

    Exploring new technologies like blockchain and cloud AI while continuing work on important long-term challenges like quantum computing.

    400:

    number of customers the company has worked with on blockchain applications

    Company Details
  • 47

    Why

    Building out its advertising business by partnering with Viacom to sell ads and with Nielsen for marketing campaign data.

    10 billion

    Number of videos that are seen on the app every day.

    Company Details
  • 48

    Why

    Its fast-growing cloud business has reduced the software giant’s reliance on PC sales. Its expanding team of quantum computing experts hopes to develop commercially viable products to compete with efforts by Google and IBM.

    $15 billion:

    projected annual revenue for its commercial cloud business

    Company Details
  • 49
  • 50

    Why

    162,037

    Number of active Uber drivers as of December 2014

    Company Details