Skip to Content
Biotechnology

Three paralyzed men have walked again after receiving electric jolts to the spine

October 31, 2018

Three men with severe spinal cord injuries have walked for the first time in years after receiving targeted electrical stimulation of the spinal cord. 

Breakthrough: Spinal cord injuries can severely reduce a person’s range of motion or lead to complete leg paralysis. In two new papers published in Nature and Nature Neuroscience, researchers describe implanting electrical stimulators into the damaged spinal cords of three men who all had partial or complete lower-leg paralysis. The stimulators then delivered targeted electric pulses in time with the patients’ walking gait.

The patients wore a series of sensors on their legs and feet that wirelessly communicated to the stimulators as they began to walk. Within a week, the men were able to leave the treadmill and walk on the ground with continued electrical stimulation. After a few months, they regained the ability to walk without any electrical stimulation at all.

Right place, right time: The authors believe their success is a result of the implants’ targeted and timed pulse delivery, which helps patients feel as though the signals are coming from their legs. Previous stimulation studies administered pulses in a way that made it difficult for patients to correctly perceive their limbs.

Progress: The paper follows another advance in September, in which researchers began testing an implanted electrical stimulator and successfully enabled a paralyzed man to walk the length of a football field. Now that the approach has been validated in several individuals, the hope is that it will lead to the development of similar neurotechnologies.

Deep Dive

Biotechnology

Sam Altman invested $180 million into a company trying to delay death

Can anti-aging breakthroughs add 10 healthy years to the human life span? The CEO of OpenAI is paying to find out.

Forget designer babies. Here’s how CRISPR is really changing lives

The gene-editing tool is being tested in people, and the first treatment could be approved this year.

Neuroscientists listened in on people’s brains for a week. They found order and chaos.

The study shows that our brains exist between chaos and stability—a finding that could be used to help tweak them either way.

More than 200 people have been treated with experimental CRISPR therapies

But at a global genome-editing summit, exciting trial results were tempered by safety and ethical concerns.

Stay connected

Illustration by Rose Wong

Get the latest updates from
MIT Technology Review

Discover special offers, top stories, upcoming events, and more.

Thank you for submitting your email!

Explore more newsletters

It looks like something went wrong.

We’re having trouble saving your preferences. Try refreshing this page and updating them one more time. If you continue to get this message, reach out to us at customer-service@technologyreview.com with a list of newsletters you’d like to receive.