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MIT Technology Review

AI that describes how yeast works will help scientists model biology better

A machine-learning algorithm fully describes how the cells function, and could help us simulate medical research more accurately.

Background: Virtually all AI systems are black boxes—algorithms that are  impossible for us to examine. That’s fine for, say, tech firms doing image recognition, but biologists would like to understand what algorithms are doing, or it’s hard to know whether to trust them.

The news: IEEE Spectrum reports that researchers mapped all the functions of brewer’s yeast—a well-studied single-cell organism—to a neural network. That lets them understand how the AI describes biological behavior, making it a reliable research tool.

Why it matters: The algorithm has already given researchers new insight into the cell biology of yeast. Applied to human cells, it could spur advances by allowing researchers to simulate personalized treatments and discover new drugs.

But: Going from yeast to human cells will be tough. And the same problem that bugs computer scientists—a need for data—will frustrate medical researchers trying to hone complex human models. Of course, one day we might be able to just design genomes on computer screens.