The recent furor over the drug company Mylan jacking up the price of lifesaving EpiPens has brought out the biohackers. A team of DIY enthusiasts calling themselves Four Thieves Vinegar have published plans that will allow anyone to build a device to self-inject epinephrine on the cheap.
EpiPens are meant as a last-ditch measure to ward off anaphylaxis—a potentially fatal allergic reaction that can result from exposure to anything from peanuts to insect stings. The drug itself is over 100 years old, but the device makes it easy for anyone to inject, which is an attractive proposition when flirting with death.
The pharmaceutical company Mylan, which is the only manufacturer of the device, was recently shown to have raised the prices of a single device from $57 to $318—that’s a 461 percent increase—since acquiring rights to it in 2007. The backstory is a bizarre tale that involves corporate greed, Congress, and Sarah Jessica Parker. Sadly, the cost prevents some people from having access to an incredibly reliable way to treat anaphylaxis.
There are several reasons why nobody else has built an alternative to the EpiPen, among them patent protection, fear of creating a device that doesn’t work reliably, and a regulatory process that makes getting products to market incredibly difficult.
Mylan did bow (a little) to public pressure, announcing a new generic EpiPen that costs $150 for a single device. But industry insiders have suggested that the components of an EpiPen cost only around $30.
And Four Thieves Vinegar, a collective that was founded to create tools for DIY medicine, has now shown that to be accurate.
The group has published a video and instructions online in which it demonstrates how to build a home-brew version of the device. They call it the EpiPencil. The team claims that it can “be built entirely using off-the-shelf parts, for just over $30.” It pairs an existing auto-injector for diabetes sufferers with regular hypodermic needles. There is, of course, the small matter of sourcing the drug that puts the “epi” in the EpiPencil—but that can be obtained under prescription or online from a chemical supplier.
It’s worth noting that while it may be possible to make such a device at home, it’s completely unregulated. Using one to treat a person for anaphylaxis would not necessarily be a good idea. But as proof that Mylan’s pricing is inflated, there’s no denying its validity.
Meet Altos Labs, Silicon Valley’s latest wild bet on living forever
Funders of a deep-pocketed new "rejuvenation" startup are said to include Jeff Bezos and Yuri Milner.
We reviewed three at-home covid tests. The results were mixed.
Over-the-counter coronavirus tests are finally available in the US. Some are more accurate and easier to use than others.
The miracle molecule that could treat brain injuries and boost your fading memory
Discovered more than a decade ago, a remarkable compound shows promise in treating everything from Alzheimer’s to brain injuries—and it just might improve your cognitive abilities.
This is how your brain makes your mind
Your mind is in fact an ongoing construction of your brain, your body, and the surrounding world.
Get the latest updates from
MIT Technology Review
Discover special offers, top stories, upcoming events, and more.