Skip to Content

Making Bioartificial Hearts

An ingenious method for making new organs could one day revolutionize medical transplants.
A pig’s heart in formaldehyde has been stripped of its cells using a strong chemical detergent. The extra­cellular matrix left behind will be seeded with cells to produce a new heart.
A rat heart in a bioreactor has been chemically stripped of cells and then repopulated with neonatal cardiac myocytes. Suspended in the bioreactor, the new heart receives nutrients; mechanical and electrical cues train it to beat on its own.
A close-up of the rat heart in the bioreactor shows that it is attached to two catheters responsible for the inflow and outflow of a nutrient solution. The heart is also hooked to two electrodes that train it to contract and expand.

Keep Reading

Most Popular

Here’s how a Twitter engineer says it will break in the coming weeks

One insider says the company’s current staffing isn’t able to sustain the platform.

Technology that lets us “speak” to our dead relatives has arrived. Are we ready?

Digital clones of the people we love could forever change how we grieve.

How to befriend a crow

I watched a bunch of crows on TikTok and now I'm trying to connect with some local birds.

Starlink signals can be reverse-engineered to work like GPS—whether SpaceX likes it or not

Elon said no thanks to using his mega-constellation for navigation. Researchers went ahead anyway.

Stay connected

Illustration by Rose Wong

Get the latest updates from
MIT Technology Review

Discover special offers, top stories, upcoming events, and more.

Thank you for submitting your email!

Explore more newsletters

It looks like something went wrong.

We’re having trouble saving your preferences. Try refreshing this page and updating them one more time. If you continue to get this message, reach out to us at customer-service@technologyreview.com with a list of newsletters you’d like to receive.