Skip to Content

Vive La Difference

From the Editor in Chief

Walk down a crowded street in just about any major U.S. city (and many others around the world) and you will encounter people who speak a panoply of languages and whose skin colors span a broad range of tones. Depending on where you live and work, you might enjoy the same rich mosaic in your neighborhood, office, and schools. We celebrate such diversity, because it opens people’s minds to different cultures and works to break down barriers of distrust and ignorance that too often divide people of varying backgrounds.

But contemporary society’s embrace of diversity comes with an element of caution and even discomfort. Especially with issues that touch upon race, we seem reluctant to probe too closely-in both the social and scientific spheres. The revolution in genomics, however, which is describing our DNA in exacting detail, is almost forcing scientists to confront differences between the world’s population groups. And not being afraid to ask potentially controversial questions about our differences is what makes this issue’s article “Genes, Medicine, and the New Race Debate” so compelling.

Written by TR executive editor David Rotman, it’s the story of a $100 million effort called the International HapMap Project. A natural extension of the Human Genome Project, which produced a master copy of the human DNA sequence, the HapMap Project aims to identify common variations in people’s DNA that seem to act as signposts for such debilitating diseases as diabetes, hypertension, and schizophrenia. If successful, the project will make it possible to assess an individual’s risk factors for these diseases as well as identify the drugs that will likely work for him or her.

But here’s the catch. In order for the HapMap to be truly relevant to people everywhere, it will have to spell out in great detail the genetic variations between people from different regions of the world. And bioethicists, sociologists, and other scientists are rightfully concerned that this genetic information could, as our story states, “be manipulated to give an air of biological credence to ethnic stereotypes, to revive discredited racial classifications, and to fuel bogus claims of fundamental genetic differences between groups.”

The HapMap researchers are walking a tightrope. The project will almost inevitably find some genetic differences between population groups: this is part of the diversity we celebrate. It’s valuable, even vital, to explore these differences, so long as we do so without reverting to old racial or ethnic stereotypes.

The HapMap effort is showing encouraging sensitivity on this point. Before even embarking on this quest, organizers formed the Population and Ethical, Legal, and Social Implications Group. Consisting of 19 well-known social scientists and genomics researchers, the group worked hard to ensure the project was conducted in an open fashion, with donors fully understanding the issues behind it (HapMap information will be publicly available on the Web).”From the very beginning, there’s been a lot of concern that this be done in as good a way as is possible,” says Ellen Wright Clayton, director of Vanderbilt University’s Genetics and Health Policy Center and cochair of the ethics group. Now, she says, as the project expands, the group is being reconfigured to become even more international and reflective of the people it touches.

The HapMap project is of immense potential benefit to people of all backgrounds. So long as investigators go forward as responsibly as they have begun, society has nothing to fear from what it reveals.

Keep Reading

Most Popular

conceptual illustration of a heart with an arrow going in on one side and a cursor coming out on the other
conceptual illustration of a heart with an arrow going in on one side and a cursor coming out on the other

Forget dating apps: Here’s how the net’s newest matchmakers help you find love

Fed up with apps, people looking for romance are finding inspiration on Twitter, TikTok—and even email newsletters.

computation concept
computation concept

How AI is reinventing what computers are

Three key ways artificial intelligence is changing what it means to compute.

still from Embodied Intelligence video
still from Embodied Intelligence video

These weird virtual creatures evolve their bodies to solve problems

They show how intelligence and body plans are closely linked—and could unlock AI for robots.

We reviewed three at-home covid tests. The results were mixed.

Over-the-counter coronavirus tests are finally available in the US. Some are more accurate and easier to use than others.

Stay connected

Illustration by Rose WongIllustration by Rose Wong

Get the latest updates from
MIT Technology Review

Discover special offers, top stories, upcoming events, and more.

Thank you for submitting your email!

Explore more newsletters

It looks like something went wrong.

We’re having trouble saving your preferences. Try refreshing this page and updating them one more time. If you continue to get this message, reach out to us at customer-service@technologyreview.com with a list of newsletters you’d like to receive.