Ed Boyden, an Assistant Professor, Biological Engineering, and Brain and Cognitive Sciences at the MIT Media Lab, will give a presentation on using light to study and treat brain disorders at 3.30pm on Wednesday at EmTech 2010. Watch a live feed of the session here.
The last few decades have seen a surge of invention of technologies that enable the observation or perturbation of information in the brain. Functional MRI, which measures blood flow changes associated with brain activity, is being explored for purposes as diverse as lie detection, prediction of human decision making, and assessment of language recovery after stroke. Implanted electrical stimulators, which enable control of neural circuit activity, are borne by hundreds of thousands of people to treat conditions such as deafness, Parkinson’s disease, and obsessive-compulsive disorder. And new methods, such as the use of light to activate or silence specific neurons in the brain, are being widely utilized by researchers to reveal insights into how to control neural circuits to achieve therapeutically useful changes in brain dynamics. We are entering a neurotechnology renaissance, in which the toolbox for understanding the brain and engineering its functions is expanding in both scope and power at an unprecedented rate.
This toolbox has grown to the point where the strategic utilization of multiple neurotechnologies in conjunction with one another, as a system, may yield fundamental new capabilities, both scientific and clinical, beyond what they can offer alone. For example, consider a system that reads out activity from a brain circuit, computes a strategy for controlling the circuit so it enters a desired state or performs a specific computation, and then delivers information into the brain to achieve this control strategy. Such a system would enable brain computations to be guided by predefined goals set by the patient or clinician, or adaptively steered in response to the circumstances of the patient’s environment or the instantaneous state of the patient’s brain.
Some examples of this kind of “brain coprocessor” technology are under active development, such as systems that perturb the epileptic brain when a seizure is electrically observed, and prosthetics for amputees that record nerves to control artificial limbs and stimulate nerves to provide sensory feedback. Looking down the line, such system architectures might be capable of very advanced functions–providing just-in-time information to the brain of a patient with dementia to augment cognition, or sculpting the risk-taking profile of an addiction patient in the presence of stimuli that prompt cravings.