Select your localized edition:

Close ×

More Ways to Connect

Discover one of our 28 local entrepreneurial communities »

Be the first to know as we launch in new countries and markets around the globe.

Interested in bringing MIT Technology Review to your local market?

MIT Technology ReviewMIT Technology Review - logo

 

Unsupported browser: Your browser does not meet modern web standards. See how it scores »

{ action.text }

The protein is a telltale sign of not only lung-cancer cells, but also many other kinds of cancer, including that of the liver, brain, prostate, and gastrointestinal tract, says Wands. Members of a group at high risk for a particular kind of cancer should, if they have HAAH in their blood, be further screened for the cancer, says Wands.

Panacea is also developing therapeutics that target the HAAH protein. The company has licensed rights to an antibody to the protein that was developed by K. Dane Wittrup, a chemical engineer at MIT. He says that antibody targeting “works like a bull’s-eye,” interfering with the target cell’s activity or causing an immune reaction against the tumor. Wittrup says that preclinical tests have shown good results when the antibody is administered to mice with tumors overexpressing HAAH, and that the company is recruiting patients for early clinical trials. He notes that these results are particularly promising for cancers for which there are currently no good therapies, such as that of the pancreas.

2 comments. Share your thoughts »

Credit: Tek Image / Photo Researchers, Inc.

Tagged: Biomedicine, cancer, MIT, disease, blood

Reprints and Permissions | Send feedback to the editor

From the Archives

Close

Introducing MIT Technology Review Insider.

Already a Magazine subscriber?

You're automatically an Insider. It's easy to activate or upgrade your account.

Activate Your Account

Become an Insider

It's the new way to subscribe. Get even more of the tech news, research, and discoveries you crave.

Sign Up

Learn More

Find out why MIT Technology Review Insider is for you and explore your options.

Show Me