A rotating three-dimensional view of an HIV infected T cell (green) forming virological synapses with three healthy CD4+ cells (red). The viral structural protein, shown in green, accumulates in button-shaped structures at the contact sites.
This movie shows high speed imaging of HIV transfer across a virological synapse. The video begins with a still view of two T cells with transmitted light and an outline of a spot where a synaptic button has formed between them. The movie then shows the movement of fluorescent viral protein into the synaptic button, followed by transfer of material from the button into the target cells. Note the movie focuses on the movement of the viral protein without indicating the outlines of the recipient cell.
The video shows a cell that has engaged in a synapse becoming infected days later. Infection was captured by continuous long term imaging over 3 days. The HIV green fluorescence image is presented on the left while an overlay of green fluorescence and bright field image is shown on the right. Images were acquired every 10 minutes over 67 hours.
The Gravity field and steady-state Ocean Circulation Explorer (GOCE) is a new satellite developed by the European Space Agency to measure the earth’s gravity field. Here, researchers discuss the mission and how it will impact climate-change research.