When is it time to say "no" to innovation? When are innovations so destabilizing that society must intervene? To raise this question isn't to launch down the path toward Luddism. The idea that innovators work under limits isn't new. The great military innovations of World War II spawned legal and practical prohibitions on what could be done with nuclear and biochemical weapons. Medical and pharmaceutical technologies are routinely regulated. So are cars, planes and other transport innovations.

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