Technology Review - Published By MIT
Advertisement

TR Editors' blog

Insights, opinions, and our editors' analysis of the latest in emerging technologies.

Blog Topics

Recent Posts

Recent Comments

  • medison : Have you considered Green Damn It and biz as usual in China?  Mandatory. Not mandatory. Mandatory...
  • jmaximus9 : The only thing this will do is send the last vestige of American manufacturing to China and...
  • gognod : Why should an employee have to spend an extra 2.5 hours a week at the office and not get paid for...
  • chir0pter : hahahaha
  • jjbaulikki : "While cautioning that the Berlin case could be a fluke" well of course it could be a Fluke
  • plasticdoc : Even though US politicians are aware of European failures in similar policies,they will repeat...
  • Siroilas : I hope you were not serious about altering the gene expression of animals just to create more...
  • danbloom : Do we need a new word for the kind of reading we do on a screen?  by Danny Bloom OPED  "Do we...
  • ... : Hopefully the use of composites in structural elements is not a mistake, but thanks for catching...
  • ... : although the 787 is the first to use composites for a majority of the critical aircraft surfaces...
Advertisement
Wednesday, June 11, 2008

Genetic Tests Already Becoming Obsolete

By Emily Singer

Genetic testing may be even worse than flat screens when it comes to the speed at which they become out of date. Last fall, I took a genetic test for a recently identified genetic variation linked to a significantly increased risk of type 2 diabetes. With a family history of the disease and other risk factors, I was curious about my own genetic status. Fortunately, I didn't have that high-risk allele--but given my family history, I likely have other disease-linked variants.

At the Beyond Genome conference in San Francisco yesterday, I discovered that the test I took a year ago now screens for four genetic variants that boost risk for the disease. Those new additions are part of a flood of genome-wide association screens that have been reported over the past year. The rate may slow down as variants with the biggest impact on common diseases are identified.

The test I took was focused on a single disease, type 2 diabetes. Genome-wide screens, such as those offered by Navigenics, DeCode, and 23andMe, offer updates--either included in the initial fee or for an annual subscription--to their customers as additional information becomes available.

The issue led to an interesting panel discussion about who is responsible for tracking patients who do show an increased risk for disease. The problem is so new that there is no consensus yet. But Steve Murphy, founder of the personalized-medicine practice Helix Health, argued that it is the physician's job, just as it is his or her responsibility to make sure that patients with high cholesterol and other risk factors are properly monitored.

Here's an unrelated but fascinating fact that you may have heard before: a full 10 percent of fathers may not be the biological parent of their children, according to Charles Lee, director of cytogenetics at the Harvard Cancer Center. Lee's group didn't set out to examine these rates specifically--researchers do paternity testing as part of their standard genetic-testing process. In the process, they discovered that one in ten men are not the biological fathers of their children.

Advertisement

Comments

  • Responsibility
    I think its funny that Murhpy thinks it is the doctors responsibility monitor and track anyones predisposition to disease.  Next time I buy a car I'm going to tell the Dealer that it is their responsibility to make sure I never run out of gas.

    People need to take responsibility for their own health.  If they are predispositioned to have diabetes they should be responsible for getting excersize and eating healthy.  Its not the doctors fault if the person sits around and eats rich foods until they develop insulin resistance.

    Just my opinion...
    Rate this comment: 12345

    zifos
    06/17/2008
    Posts:11
    Avg Rating:
    4/5
Advertisement

Log In

Forgot your password?     Register »
Advertisement
Technology Review July/August 2009

Current Issue

Search Me
Inside the launch of Stephen Wolfram’s new “computational knowledge engine.”
•  Subscribe
Save 41%
•  Table of Contents
•  MIT News
» Gift Subscription
» Digital Subscription
» Reprints, Back Issues
» Subscribe
» Table of Contents
» MIT News

More Technology News from Forbes

Advertisement
MIT Massachusetts Institute of Technology © 2009 Technology Review. All Rights Reserved.