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Liver Scaffold: The network of blood vessels in a decellularized liver (left) looks the same as that in a normal one (right).
Credit: B.E. Uygun and O.B. Usta
Growing New Livers
Scaffold from damaged organs may provide the basis for new ones.
Source: "Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix"
Basak Uygun et al.
Nature Medicine 16: 814-820
Results: Researchers at Massachusetts General Hospital, in Boston, grew new livers by removing the cells from an existing rat liver and seeding the scaffold left behind with healthy liver cells. The new organs were able to function for a short time when transplanted into rats.
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