Shock treatment: These images show blood flow in the left ventricle of a 62-year-old patient’s heart (red indicates blood flow). The images on the left show the ventricle before acoustic shockwave treatment; the ones on the right show it after treatment.
R. Erbel, Essen University, Germany

Biomedicine

Shocking Treatment for Heart Repair

A device sends shockwaves to prompt blood vessel growth.

  • Thursday, May 20, 2010
  • By Lauren Gravitz

Cardiac patients are living longer and longer--up to 20 years after receiving stents, a heart bypass, or heart-valve replacements. But extended lifespan is often accompanied by other complications, as a repaired heart can still have difficulty getting enough oxygen. The accompanying pain, a squeezing pressure in the chest called angina, can plague patients for years, and there are some for whom no surgery can provide relief. But a noninvasive shockwave machine could help prompt the growth of new blood vessels, restoring the heart's oxygen supply and alleviating the pain.

In a clinical trial at three centers across the United States, cardiologists are testing the safety of the shockwave device, developed by Maryland-based Medispec. The "Cardiospec" machine is based on the same sound-wave technology used to break up kidney stones, but it requires only about one-tenth the energy. "Shock waves are acoustic waves that create pressure that can be focused," says Medispec's Gil Hakim, the company's director of new product development. Direct that pressure toward the heart muscle with just the right intensity, and it causes the body to produce new blood vessels.

Researchers aren't sure precisely why shockwaves have this effect--they believe that the pressure may induce a cascade of events that mimic wound-healing, recruiting undifferentiated cells to the area to build blood vessels. Preliminary studies show that about 70 percent of the patients who undergo the shockwave procedure experience somewhere between a 60 to 70 percent improvement in blood flow to their hearts.

"Patients with [recurring] angina consume a lot of medical care because they have multiple emergency visits, they have multiple angiograms, and their quality of life is extremely low," says Amir Lerman, a cardiovascular specialist at the Mayo Clinic in Rochester, MN, who's heading up the Cardiospec trial. And, he notes, the treatments available to these patients to date are short-term therapies that address the symptoms rather than the cause. "These patients currently don't have any alternative solution. And we need to find one because they live a long time."

Advertisement

The trial will recruit 15 patients--five each at the Mayo Clinic, the University of California at San Diego, and Albert Einstein Medical Center in Philadelphia--and it will consist of nine treatments applied over a nine-week period (three treatments per week during weeks one, five, and nine).

Print

Related Articles

Busting Blood Clots with Sound Waves

New technology being tested could provide a noninvasive approach to treating stroke.

Towards Creating Blood Vessels

Scientists find a better way to make more of the cells that make blood vessels.

Better Blood Vessels

New artificial blood vessels could help a wider range of patients.

Close Comments

To comment, please sign in or register

Forgot my password

blankster

1 Comment

  • 629 Days Ago
  • 05/20/2010

Researchers aren't sure precisely why shockwaves have this effect

If you have not read "Vibrational Medicine" by Dr. Richard Gerber, do so. Our bodies, at the quatum level, are vibrations. Dr. Gerber provides numerous clinical examples where treatments focused on the subatomic level are quite effective and successful.  To quote Dr. Gerber from an interview, "The vibrational approach, especially the subtle energy medicine approach, works by injecting selective frequencies of energy into the body that encourage the body’s own self-healing systems to do the work".

Reply

Advertisement

MAGAZINE

Can We Build Tomorrow's Breakthroughs?

Manufacturing in the United States is in trouble. That's bad news not just for the country's economy but for the future of innovation.

Videos

The Virtual Nurse Will See You Now

More

Advertisement

Technology Review Lists

TR50

Our list of the 50 most innovative companies, including the following:

Toyota

Pacific Biosciences

Akamai

ARM Holdings

More

Advertisement

Facebook

Advertisement