Cancer killer: A cross-¬section of a polymer matrix designed to prime the immune system against cancer.
Credit: Courtesy of Edward Doherty, Omar Ali, and Microvision Labs
New publications, experiments and breakthroughs in biomedicine--and what they mean.
An Anti-Cancer Implant
A polymer disc triggers an immune attack to shrink tumors
Source: "In Situ Regulation of DC Subsets and T Cells Mediates Tumor Regression in Mice"
David J. Mooney et al.
Science Translational Medicine 1(8): 8ra19
Results: An implantable disc acts as a therapeutic vaccine against cancer, triggering the immune system to attack malignant cells. It slowed cancer growth and increased survival time in mice with melanoma tumors. The cancers completely disappeared in 20 to 50 percent of animals given two vaccinations; the success rate depended on how long the tumors had been growing.
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