Better by design: Four helices form the backbone of a man-made protein.
Credit: Dutton Lab
New publications, experiments and breakthroughs in biomedicine--and what they mean.
Artificial Proteins
A synthetic protein built from scratch can carry oxygen, mimicking blood
Source: "Design and engineering of an O(2) transport protein"
P. Leslie Dutton et al.
Nature 458: 305-309
Results: Scientists at the University of Pennsylvania have designed and built a protein that can transport oxygen. The protein is much simpler than the oxygen-carrying proteins found in nature, and the process that they used demonstrates a new method for making novel proteins.
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