When a small slice of a cell with integrins labeled (top) is viewed in cross section (bottom), the three-dimensional organization of the molecules is revealed. Red and yellow areas are closest to the glass cover slip on which the sample has been placed; the yellow regions show areas where the integrins have attached to the glass. The networks of integrins seen in blue and purple are inside the cell where new proteins are being made.
Credit: Howard Hughes Medical Institute
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