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September 2004

Translating Iceland's Genes into Medicine

Armed with the DNA of an entire nation, deCode Genetics is shaving years off the drug discovery process.

By Corie Lok

Reclined in a chair at a clinic outside Reykjavik, Iceland, Benedikt Arnason tells the story of the day, 11 years ago, that he had a heart attack. In a deep, rich voice cultivated by years as a stage actor and director with Iceland's national theater, he describes the chest pain that gripped him after one performance. He got to the hospital just in time. "The last thing I remember is the doctor asking me about my medical history," Arnason says. When he woke up, he found burn marks across his chest. Doctors had shocked him back to life. Now Arnason comes every two weeks to this suburban clinic, so doctors can monitor his progress as a participant in a trial of a new experimental drug -- one that physicians hope might spare him from having a second, and possibly deadly, heart attack.

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