September 2000
A Genetic Rx for Rejection
Biotechnology: Gene screens determine transplant treatment
By Erika Jonietz
Organ transplant patients face a catch-22. The powerful drugs that suppress their immune systems and protect their new organs from rejection can cause life-threatening side effects, including high blood pressure, susceptibility to infection and even cancer. Now researchers at the University of Pittsburgh Medical Center have found a link between a patient's genes and the chances of rejection that could free many patients from lifelong dependence on immunosuppressant drugs.
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