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January 2000

A Death in Philadelphia

An experimental gene-therapy treatment kills an eighteen-year-old volunteer in a clinical trial. Is this the final blow for a much-beleaguered technology?

By Stephen S. Hall

As many would-be biotech entrepreneurs have learned, one of the scariest things about bringing a new biomedical technology into the world is when an unexpected and very public problem crops up, especially during clinical trials. You can't tell if you've merely hit a bump in the road or run smack into a brick wall. At the moment of impact, they feel much the same.

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