Select your localized edition:

Close ×

More Ways to Connect

Discover one of our 28 local entrepreneurial communities »

Be the first to know as we launch in new countries and markets around the globe.

Interested in bringing MIT Technology Review to your local market?

MIT Technology ReviewMIT Technology Review - logo


Unsupported browser: Your browser does not meet modern web standards. See how it scores »

{ action.text }

Impressive Chips

By helping to identify the proteins involved in fundamental cellular reactions, protein chips could become powerful aids in disease diagnosis. Aspira Biosystems, a startup in South San Francisco, CA, has developed a way to make protein chips that are more reliable and can detect more proteins than existing chips. Most of today’s protein chips rely on nanoscopic spots of special proteins to interact with and capture other proteins. Because the molecules are so finicky, however, chips are available for only a few types of proteins. Aspira’s system lets researchers make casts of short fragments of proteins in a polymer; these casts, arrayed on a chip, can selectively capture the matching proteins from a mixture of molecules. Using this technique, it should be possible to make chips that can latch onto virtually any protein, making way for the diagnostic tests that are needed to make personalized medicine a reality. Next year Aspira plans to begin selling the chips to pharmaceutical and biotechnology companies for use in drug discovery; diagnostic applications will follow.

0 comments about this story. Start the discussion »

Tagged: Web

Reprints and Permissions | Send feedback to the editor

From the Archives


Introducing MIT Technology Review Insider.

Already a Magazine subscriber?

You're automatically an Insider. It's easy to activate or upgrade your account.

Activate Your Account

Become an Insider

It's the new way to subscribe. Get even more of the tech news, research, and discoveries you crave.

Sign Up

Learn More

Find out why MIT Technology Review Insider is for you and explore your options.

Show Me