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March 2007

Nanocosmetics: Buyer Beware

Continued from page 1

By Apoorva Mandavilli

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Check the Label

According to the Project on Emerging Nanotechnologies, which is run by the Woodrow Wilson International Center for Scholars in Washington, DC, nearly 400 products on the market claim to use nanotechnology, and 64 of those are cosmetics. And yet no one in the federal government is responsible for overseeing the safety of nanotechnology. "People are miniaturizing the particles, nanosizing them," says Andrew Maynard, science advisor for the Woodrow Wilson project, but he says that companies don't necessarily recognize the risks associated with the unique properties of nanoparticles.

That nanoparticles have unique properties is, of course, exactly the point of using them. When particles of some materials become extremely small, they can exhibit unusual--and interesting--physical and chemical characteristics. Gold nanoparticles, for example, are red and are much more reactive than larger chunks of the metal. Nanoparticle versions of some ingredients used in cosmetics are more stable, improve product texture, and are absorbed better.

Titanium dioxide and zinc oxide, which have been used for decades in sunscreens, are two examples of substances that benefit from nano­technology. Normally, each material forms a thick whitish coating, but nanosizing their particles makes them translucent--and, naturally, more popular among consumers. Some cosmetics companies use other nanoparticles, such as the 60-carbon soccer-ball-shaped molecules known as fullerenes or buckyballs. Zelens, a company based in London, England, claims that fullerenes in its skin cream help to suck up free radicals and slow aging.

But here's the rub: though some nanomaterials clearly have advantages, such materials might also pose risks. Will the smaller particles penetrate the skin? Can they clog airways and trigger immune responses? Will they lodge in the body's tissues, including the brain?

The simple answer is that no one knows. The U.S. Food and Drug Administration, the Environmental Protection Agency, and other federal agencies have research programs in place that may eventually answer some questions about the toxicity and environmental impact of nanoparticles. But such research will take time and a great deal more money. Through the federal government's National Nano­technology Initiative, the United States has spent an estimated $6.5 billion on various types of nanotechnology research, but only 4 percent of last year's budget went to assessing potential risks. In the meantime, the best the FDA can do is to say it has "no evidence at present to suggest that any of the materials currently in use pose a major safety concern."

Nano Mysteries

Unlike pharmaceuticals, cosmetics don't have to pass safety tests before they are sold. Cosmetics companies are free to sell their products without such testing--at least until a problem crops up. And so far, nanoparticles used in cosmetics seem to have a clean record.

John Bailey, executive vice president for science at the Cosmetic, Toiletry, and Fragrance Association, an industry trade group in Washington, DC, points out that sunscreens using titanium dioxide and zinc oxide nanoparticles have been used "safely and effectively by consumers for decades" and have been reviewed and approved by the FDA. But whether that record of safety can be extrapolated to other nanoparticles in other types of cosmetics is less certain. The danger is that conventional safety tests for cosmetics and other products might not pick up the special risks nanoparticles pose.

March/April 2007

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Comments

  • Incorrect "Scare" Article
    ashalleck on 03/12/2007 at 9:38 AM
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    This is a very biased, unsupported article and I'm surprised it was printed.  This is one person who is afraid to use a product that is in general distribution with no adverse affects.

    The FDA and the nanotech industry, currently led by scientists and businessmen (not hucksters) with children and grandchildren, have been amazingly responsible and self policing if this author had done the slightest bit of research other than a few superficial calls. In fact, the nanotech industry has been a model of concern and care about possible effects of their poducts because no one in the industry wants another GM market crisis.  The Nanobusiness Alliance, the industry trade organization run by Sean Murdoch (ex-McKinsey star), has testified in front of Congress to obtain more funds to do long term nanotech eco/evironment/health studies. Meanwhile the FDA has applied existing rules to all nanotech products ... so far quite successfully ... and there have been no - I repeat - no instances or studies that have successfully implecated any marketed nanoproduct in any societal negative impact.  The danger is that these "scare" articles are imprecise and don't reflect what is really going on in the nanoworld. I write about the nanoworld every month in a newsletter called "NanoClarity", am one of its experienced critics,am  an MIT grad, and if any bad stuff was really happening, I'd be all over it.  My only advice to the author is use the product you paid over $100 in it. It has no nanotech in it as we define it and your cry here, although in theory is one many in the industry have already addressed, don't slam an entire industry by your single data point on a curve that is really being well defined. Last, I call your attention to the recent Dupont/Evironmental Defense draft safety roadmap and last fall's FDA nanotech safety meeting. If you had researched any of these, you would probably not written this article or have written it in a much more responsible way.
    Rate this comment: 12345
    • Re: Incorrect
      clemrod on 03/28/2007 at 6:12 AM
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      1
      Good comments.  So how on earth did a cosmetics scam arrive in Technology Review?  Someone on the editorial staff must be desperately lazy, and nearly as lacking in nanotech understanding as the author of the article.
      Rate this comment: 12345
  • Re: incorrect
    Bill Hillary on 03/28/2007 at 9:24 AM
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    1/5
    Nanoparticles are awesome.  I got one stuck in my eye for three days once and I could like see really good out of that eye. I wood have done it again, but I lost the rest of the nanobot in my back yard.  I think the dog barried it.

    The editor is just scared of cool stuff, thats all.  Maybe if he'd grow a pair of sox than he'd get it!
    Rate this comment: 12345
  • Mesothelioma
    keiran on 03/29/2007 at 12:47 AM
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    2
    Yep all technology is good, there is no moral component to science and we've never seen any problems with small particles and biological systems.  Or you could try googling James Hardy Industries, asbestos and mesothelioma.  It took about 40 years for the evidence to become unambiguous.
    Rate this comment: 12345
  • Nonsense
    malvido on 03/29/2007 at 10:57 AM
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    1
    Articles like this make me wonder about the rest of the articles.
    Rate this comment: 12345
    • Re: Nonsense
      prawin on 04/02/2007 at 9:44 PM
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      5/5
      This is a perfectly good article that raises valid questions. It is known that chemicals exhibit abnormal properties in nano-size, [different from nano-concentration]. The effects of such chemicals haven't been studied, but products with such chemicals have been sold to unsuspecting customers who have nowhere to turn for further information. And, there is no regulatory body who can police the industry on the issue.

      This article asks all the right questions.
      Rate this comment: 12345
  • Bionova
    heidiswiss on 04/22/2007 at 9:51 PM
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    I have been using Bionova for 2 years and see dramatic improvement in my skin.  The reviewer casts doubts on herself by her unwillingness to try the product. 

    I will continue to use this product.
    Rate this comment: 12345
  • Bionova is great!!
    wise&smart on 04/23/2007 at 1:27 AM
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    1
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    5/5
    My skin has totaly changed since I started using Bionova!I can leave without foundation now and I am not ahamed of my skin..No more acne & blemishes.
    I think the article is poorly written and the author have not tried the product...
    Rate this comment: 12345
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