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Monday, May 1, 2006

Tiny Electrodes for the Brain

Continued from page 1

By Kevin Bullis

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Beyond use in deep brain stimulation, Llinas says his electrodes could detect signals, say, in the area of a person's brain responsible for directing arm movement. These signals could then be used to drive a robotic arm, restoring some abilities to people paralyzed by brain and spinal-cord injuries. Llinas says the first application of the nanowire electrodes may be to route nerve impulses around damaged areas of the spinal cord, either to other nerves or directly to muscles, possibly restoring function to paralyzed limbs.

The nano electrodes could also play a role in improving the cochlear implants used to restore hearing. Because the electrodes are so small, it could be possible to increase the number of electrodes used in a cochlear implant, "to stimulate a broader region and give more color to sound," says Patrick Anquetil, a mechanical engineering postdoctoral fellow at MIT and one of the researchers on the project. He says the first commercial uses of the nanowire electrodes are probably still five years away.

In the future, the researchers plan to build steerable electrodes. To do this, they will use a polymer that contracts in response to electricity. A bundle of such nanowires could be directed, by causing selected nanowires to contract.

The researchers think that, eventually, the bundle of nanowires could partly steer itself. Anquetil says they have made polymers that act as pressure sensors, and they see the possibility of using semiconducting polymers as the basis for simple electric switches. "One thing that really excites us about this is, in principle, there's no reason why, with the same material, you cannot build a whole system in which you have contraction, measurement, sensing, and computation."

While the first bundles would use relatively few electrodes, thousands could eventually be grouped together to form a package no wider than the 1-2 millimeter probes Llinas says are used today in the brain. Once near the targeted area, the nanowires would be allowed to separate. The wires would then spread out, pushed into a branching network of capillaries. This would allow researchers to monitor and deliver impulses to individual neurons deep inside the brain in a distributed area, an ability that could prove a boon to brain researchers now limited to using relatively small arrays of electrodes.

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Comments

  • Wired?  I doubt it.
    Guest (Tom Schaefer) on 05/01/2006 at 12:00 AM
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    1
    Dollars to donuts that a nano scale wireless solution will be found and overtake this.  Just consider the impedance of a very thin wire multiple centimeters in length.  I thin tis tech will have applications, but only locally within the brain, not to carry signals in and out of it.
    Rate this comment: 12345
    • Wireless
      Guest (Treehorn) on 05/18/2006 at 12:00 AM
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      1
      The issue with a completely wireless instrument is how you supply the power.  You would have to have an internal power source (battery) or external power source (a wire delivering current).  Another option would be to have a device that was inductively charged (such as an RFID chip), however without knowing the details of the voltage/current delivered for this treatment, I would think that a nano-scale instrument would not be able to provide the required power or would need an antenna that would be too big for this type of application in the brain.
      Rate this comment: 12345
  • enhancement
    Guest (nanotechbuzz.com) on 05/02/2006 at 12:00 AM
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    1
    Now the question is, where will we draw the line? Few people will argue against nanoelectrode implants for treating parkinson's, but what about implants for human enhancement? Our brains are good at some things and computers are good at others. The temptation to employ  nanotechnologies like this one to enhance our mental and phsical capabilities will be great. But is it the right thing to do?
    Rate this comment: 12345
    • Cyberpunk
      Guest (ddb) on 05/03/2006 at 12:00 AM
      Posts:
      1
      This sort of technology has "existed" in the sci-fi world for a long time.  For some it seems like a logical next step, for others an abomination.  Advances such as these are always seen as different ends of an extreme, I only hope the decision is left up to individuals and not mandated by society.
      Rate this comment: 12345
      • the divide
        Guest (turnstyle) on 05/09/2006 at 12:00 AM
        Posts:
        1
        This leads to another theme in Sci-Fi of the divide between human & post human.  We are only seeing the very start of this.  Will you be a new Quaker? or do you want to surf the web by bitting your lip?
        Rate this comment: 12345
  • Treatments for Diffuse Cerebral injury and post traumatic hydrocephalus.
    Guest (Purushotham) on 06/21/2006 at 12:00 AM
    Posts:
    1
    Hi,
    My father met an accident in 2002 and he is still in medication. doctors found his situation as Diffuse Cerebral injury, post traumatic hydrocephalus. Can anyone please tell me what are the good treatments available for his improvement?
    my mail id is arpurush@yahoo.com
    Rate this comment: 12345
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