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Saturday, July 01, 2006

Redesigning Life to Make Ethanol

Genetically engineered organisms can more efficiently produce ethanol from cheap and abundant sources of biomass, such as agricultural waste. It could make ethanol cost competitive.

By Jamie Shreeve

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Colonies of recombinant Streptomyces bacteria are designed to produce enzymes called cellulases. With these enzymes, the bacteria can break down cellulose on the way to producing ethanol. (Courtesy of NREL/U.S. Dept. of Energy/Photo Researchers)
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On January 31, Ari Patrinos was sitting in his living room in Rockville, MD, listening to the State of the Union speech and slowly nodding off. Suddenly, he was jolted awake.

"We'll also fund additional research for cutting-edge methods of producing ethanol," President Bush was saying on the television, "not just from corn but from wood chips and stalks or switchgrass. Our goal is to make this new kind of ethanol practical and competitive within six years."

Unlike most of the legislators who gamely applauded the president's words, Patrinos understood exactly what they meant. In fact, he had dashed them off himself days earlier at the harried request of his boss, unaware that they were destined for the State of the Union speech. Patrinos, then associate director of the U.S. Department of Energy's Office of Biological and Environmental Research, had been touting cellulosic ethanol as an alternative energy source for years, only to be met with indifference or ridicule. Now, it seemed, even the most petro-friendly of politicians was convinced.

Producing ethanol fuel from biomass is attractive for a number of reasons. At a time of soaring gas prices and worries over the long-term availability of foreign oil, the domestic supply of raw materials for making biofuels appears nearly unlimited. Meanwhile, the amount of carbon dioxide dumped into the atmosphere annually by burning fossil fuels is projected to rise worldwide from about 24 billion metric tons in 2002 to 33 billion metric tons in 2015. Burning a gallon of ethanol, on the other hand, adds little to the total carbon in the atmosphere, since the carbon dioxide given off in the process is roughly equal to the amount absorbed by the plants used to produce the next gallon.

Using ethanol for auto fuel is hardly a new idea (see "Brazil's Bounty"). Since the energy crisis of the early 1970s, tax incentives have pushed ethanol production up; in 2005, it reached four billion gallons a year. But that still translates to only 3 percent of the fuel in American gas tanks. One reason for the limited use of ethanol is that in the United States, it's made almost exclusively from cornstarch; the process is inefficient and competes with other agricultural uses of corn. While it is relatively easy to convert the starch in corn kernels into the sugars needed to produce ethanol, the fuel yield is low compared with the amount of energy that goes into raising and harvesting the crops. Processing ethanol from cellulose -- wheat and rice straw, switchgrass, paper pulp, agricultural waste products like corn cobs and leaves -- has the potential to squeeze at least twice as much fuel from the same area of land, because so much more biomass is available per acre. Moreover, such an approach would use feedstocks that are otherwise essentially worthless.

Converting cellulose to ethanol involves two fundamental steps: breaking the long chains of cellulose molecules into glucose and other sugars, and fermenting those sugars into ethanol. In nature, these processes are performed by different organisms: fungi and bacteria that use enzymes (cellulases) to "free" the sugar in cellulose, and other microbes, primarily yeasts, that ferment sugars into alcohol.

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Comments

  • New Crop/Process already Here
    Guest (Lee McClune) on 07/19/2006 at 12:00 AM
    Posts:
    1
    I have developed a totally new crop/process that already can produce 2 times the Ethanol as Corn, and we can produce it at ZERO FOSSIL FUEL/ENERGY Input, if
    interested, see > sorganol.com < ,
    been trying to get some Government support, but have been unable to get any help,, it not only has High Potential, it is Very Low Cost to Grow, and is drought resistant, and can be grown anywhere in the US, with no exotic chemicals/enzymes needed,,
    Sugar cane can only be grown in tropical areas,, LFM, knoxville,Ia
    Rate this comment: 12345
    • LFM: You need a new web site
      Guest (plugged in) on 07/21/2006 at 12:00 AM
      Posts:
      1
      No way to contact you on sorganol.com. I can fix that. Two good ideas...congrats.
      Rate this comment: 12345
    • Sorganol Info omitted
      Guest (Mike) on 07/21/2006 at 12:00 AM
      Posts:
      1
      Nice info, but you omitted Sugar Beets.

      Also - what temp will the ethanol boil/distill off at and at what % efficiency? Otherwise - good stuff!
      Rate this comment: 12345
    • Sorganol
      Guest (Marty Riske) on 07/24/2006 at 12:00 AM
      Posts:
      1
      How much water is required.  Ethanol processes using corn require hundreds of thousands of gallons of water daily.
      Rate this comment: 12345
    • Re: New Crop/Process already Here
      reoplan on 08/21/2006 at 5:56 PM
      Posts:
      2
      Dear Lee

      Let's chat. I'll explain all when we do.
      info@reoplan.com   or   waxman44@verizon.net
      Send me your contact information.

      Thanks,

      Alan
      Rate this comment: 12345
    • Re: New Crop/Process already Here
      sweetsorghum on 09/19/2006 at 7:36 PM
      Posts:
      1
      I can not find Mir.  Lee McClune's contact infor.  Please let me know.  I am very interested in the ideas he has.  I would ove to exchange some idea through the e-mail.

      My e-mail is flinqian@hotmail.com
      Rate this comment: 12345
    • Re: New Crop/Process already Here
      waygmcgo on 11/06/2006 at 5:29 PM
      Posts:
      1
      Mr. McClune please contact me- I would like to get some more information.
      Rate this comment: 12345
  • At least its not stem cell research
    Guest (sirlanse) on 07/21/2006 at 12:00 AM
    Posts:
    1
    The embryonic stem cell folks would have us believe that they are the cure for everything.  At least they aren't after this money.
    Rate this comment: 12345
  • Yankee-Doodlism
    Guest (Mike) on 07/21/2006 at 12:00 AM
    Posts:
    1
    What we need here is the spirit of the X Prize (for Space Flight) applied towards the ingenuity of scholars, companies and backyard inventors as to reward the creativity neccessary to overcoming obstacles like Fuel and Energy Shortages, Medical and Biological Breakthroughs etc. Hold out a $10 million dollar prize for anyone to collect is a great incentive!
    Rate this comment: 12345
    • I agree.
      Guest (Alex) on 07/23/2006 at 12:00 AM
      Posts:
      1
      I believe you hit the nail on the head.  A prize is needed to bring this research to a marketable product.  Mr. Gates and Buffett: where are you?
      Rate this comment: 12345
    • Re: Yankee-Doodlism
      Guest (Keith) on 08/02/2006 at 12:00 AM
      Posts:
      1
      Concerning technology (including bio technology) and government subsidies.

      While i generally disagree with ongoing government funded research programs ware there is little to no incentive for results and often the incentive to use up all the monies given in yearly budgets in fear that next year those budgets will be reduced, all with out regard to how well the monies are used in research.

      The use of prize monies by the government, would provide  incentives to companies to compete in areas ware the people want the country to go.
      Rate this comment: 12345
    • Re: Yankee-Doodlism
      reoplan on 08/21/2006 at 6:02 PM
      Posts:
      2
      Mike
      You are absolutely right. And, there are some business models out there that form the blueprint you suggest we need. Interestingly, the model has nothing whatsoever to do with the petroleum industry. I want to talk to Lee first. Then we'll determine which way to go. I've been down that road and I'm proud to say my thumbprint is on one of them. In this case, Yankee Doodle HAS A FARM!
      Rate this comment: 12345
  • How free is "free"?
    Guest (Jim D) on 07/23/2006 at 12:00 AM
    Posts:
    1
    What currently happens to the kilotons of "waste" that are supposed to fuel this scheme?  Whatever it is, it will be disrupted by the new technology -- here's hoping the cost of that disruption won't be a deal-killer.
    Rate this comment: 12345
    • Waste Matter
      Guest (Mike) on 07/24/2006 at 12:00 AM
      Posts:
      1
      If this solution actually works, then there should be little waste since some of the materials can be used as fodder or animal foods, some will be used as fuel to drive the ethanol distillation process, and the rest can be recycled in some type of huge compost pile. My one nagging question about the this is will the modified waste product contain organisms harmful to the natural envirionment and as animal feed?
      Rate this comment: 12345
      • [no subject]
        Guest (Sean) on 07/24/2006 at 12:00 AM
        Posts:
        1
        You'd just have to cook it a little and that should get rid of any lingering GMOs.
        Rate this comment: 12345
      • Cellulose Consumption
        Guest (John) on 07/24/2006 at 12:00 AM
        Posts:
        1
        Given that the organisms are based on the idea of converting cellulose to ethanol, and doing nothing else. I can't imagine it doing any real damage to humans, in the sense of flesh eating virus type of harm. However, while I believe we are incapable of digesting cellulose, if it got in our digestive system and survived it could potentially make us perpetually drunk?
        Either way, if it is something that can survive "in the wild", I can see it being very dangerous to crops.
        Rate this comment: 12345
  • You Left Out Syngas Fermentation
    Guest (C. Scott Miller) on 07/26/2006 at 12:00 AM
    Posts:
    1
    By gasifying your feedstock to break down the chemical bonds you can save water, time, and tons of purge disposal.  Cooling the syngas can co-generate electricity. Dr. Gaddy at BRI in Fayetteville, Ark. has created a bioreactor filled with patented bacteria that synthesize the CO and H2 into ethanol and water. The best part - the feedstock can be blended - tires, autofluff, C&D, waste, fossil fuels, MSW, etc. Try that with enzymes. Check out the process description at brienergy.com.
    Rate this comment: 12345
  • Make a food and energy system!
    Guest (R. Kellmer) on 08/07/2006 at 12:00 AM
    Posts:
    1
    It's simple to use this technique and use the land for food production.

    1. Grow the grain and harvest it. That's food for people.

    2.  Havest the stalks and use enzymes to convert to ethanol.  There's energy.

    3.  Feed the byproducts of the ethanol process to cattle or other animals.  That gives us more food.

    4.  Use the manure from the cattle to produce methane and use it to run a generator.  Sell the electricity to the power grid.
    Rate this comment: 12345
  • Cellulosic Waste
    jhawkmurph on 09/01/2006 at 10:18 AM
    Posts:
    2
    Avg Rating:
    5/5
       You erudite gentlemen are forgetting one thing:  TOC (total organic carbon),which farmers need to grow crops.  Eventually, if, as you plan, they deplete this resource,they are in trouble.
       Wood chips are suggested and are fine, but eventally, those with septic tanks, who need to convert NH3-nitrogen, to NOx-nitrogen, will be forced by EPA, et al, to compete in that deciduous market.
       But, I do like the octane route, but favor the bio-diesel route from algae (Green Fuels).    TPM
    Rate this comment: 12345
  • avoiding genetic engineering
    Cpt_Nemo on 01/22/2007 at 2:08 AM
    Posts:
    14
    Avg Rating:
    4/5
    I read in an early 90s edition of New Scientist about the fascinating organisation of slime moulds. They are veritable cities filled with harmoniously interacting species of bacteria, etc.

    A woman received a MacArthur genius award for her pioneering research on the communication pathways between bacteria.

    I believe that it is possible to find and develop a cooperative slime mould that has as its primary purpose conversion of nutrient rich fluids - the unprocessed sap from sugar cane, or other plants that have a high proportion of sugars - into ethanol. With tuning (selective breding) and creative use of microfluidics the systems could be designed to increase the ratio of ethanol to other byproducts that are unwanted. It should be arranged with the provision of an intake reservoir and also a reservoir that collects its continual output.

    In otherwords, I believe that it should mimic the urinary(ethanol output) and digestion(consuming juice to be processed)/excretion(elimination of digested material) that is found in multicellular lifeforms.
    Rate this comment: 12345
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