|
Wednesday, August 01, 2007 Making Gasoline from BacteriaA biotech startup wants to coax fuels from engineered microbes. By Neil Savage
The biofuel of the future could well be gasoline. That's the hope of one biotech startup that on Monday described for the first time how it is coaxing bacteria into producing hydrocarbons that could be processed into fuels like those made from petroleum. LS9, a company based in San Carlos, CA, and founded by geneticist George Church, of Harvard Medical School, and plant biologist Chris Somerville, of Stanford University, had previously said that it was working on what it calls "renewable petroleum." But at a Society for Industrial Microbiology conference on Monday, the company began speaking more openly about what it has accomplished: it has genetically engineered various bacteria, including E. coli, to custom-produce hydrocarbon chains. To do this, the company is employing tools from the field of synthetic biology to modify the genetic pathways that bacteria, plants, and animals use to make fatty acids, one of the main ways that organisms store energy. Fatty acids are chains of carbon and hydrogen atoms strung together in a particular arrangement, with a carboxylic acid group made of carbon, hydrogen, and oxygen attached at one end. Take away the acid, and you're left with a hydrocarbon that can be made into fuel. "I am very impressed with what they're doing," says James Collins, codirector of the Center for Advanced Biotechnology at Boston University. He calls the company's use of synthetic biology and systems biology to engineer hydrocarbon-producing bacteria "cutting edge." In some cases, LS9's researchers used standard recombinant DNA techniques to insert genes into the microbes. In other cases, they redesigned known genes with a computer and synthesized them. The resulting modified bacteria make and excrete hydrocarbon molecules that are the length and molecular structure the company desires. Stephen del Cardayre, a biochemist and LS9's vice president for research and development, says the company can make hundreds of different hydrocarbon molecules. The process can yield crude oil without the contaminating sulfur that much petroleum out of the ground contains. The crude, in turn, would go to a standard refinery to be processed into automotive fuel, jet fuel, diesel fuel, or any other petroleum product that someone wanted to make. Next year LS9 will build a pilot plant in California to test and perfect the process, and the company hopes to be selling improved biodiesel and providing synthetic biocrudes to refineries for further processing within three to five years. (See "Building Better Biofuels.") But LS9 isn't the only company in this game. Amyris Biotechnologies, of Emeryville, CA, is also using genes from plants and animals to make microbes produce designer fuels. Neil Renninger, senior vice president of development and one of the company's cofounders, says that Amyris has also created bacteria capable of supplying renewable hydrocarbon-based fuels. The main difference between the companies, Renninger says, is that while LS9 is working on a biocrude that would be processed in a refinery, Amyris is working on directly producing fuels that would need little or no further processing. |
Fuel from Waste
12/21/2007



Comments
Chad on 08/01/2007 at 11:13 AM
6
cripdyke on 08/01/2007 at 12:50 PM
14
seljo_myeri on 08/07/2008 at 3:46 PM
2
http://www.weatherquestions.com/Roy-Spencer-on-global-warming.htm
knightconsulting on 08/01/2007 at 7:36 PM
1
http://www.getfirefly.net/hydraulicpowerplant.jpg
bvz on 08/02/2007 at 3:10 AM
1
As to your hydraulic power idea... I am a bit confused. In step 4 you state that there is nothing holding the left side weight up... but it isn't up. It's down because of the water that you added previously. In fact, as long as the right side weight is "hooked" to the ceiling, the left side won't move at all. Additionally, once the right side is released it most likely won't move either because the friction in the system will overcome the minute amount of potential energy difference in the two weights. In fact, the energy used to get the water up to the height of the individual weights will result in a total net loss in the system.
It was a neat idea, but unfortunately you are fighting against some very basic laws of physics. Sorry...
seljo_myeri on 08/07/2008 at 3:53 PM
2
However, the basics are what drives hydro-power plants. The problem is that we've tapped all the practical hydro in the U.S. already. Maybe we could build a giant reservoir in the rockies that we could then drain through the turbine(s) to generate more hydro-electricity.
joefargo on 08/03/2007 at 4:26 PM
1
This is all without considering management of the crop and transport to refinery. You might have like emissions with any crop.
Additionally, we need be careful because the thermal input of choice for ethanol in the Dakotas is becoming coal instead of natural gas. Ethanol production is a new growth market for coal mines.
tyriver on 08/04/2007 at 7:46 AM
1
carb-H2 on 08/05/2007 at 3:19 PM
2
Recall 30-40 years ago, oil was cheap. the Soviet Union made single cell protein from oil not from sugars. If you tried to do everything in reverse way, you should pay poor energy efficiency for the whole system.
Time will say that it is hoax. Butanol is much better than hydrocarbon. The better solution is to make hydrogen from sugars.
carb-H2 on 08/05/2007 at 3:21 PM
2
madsci on 08/06/2007 at 9:59 PM
4
dorumi on 10/22/2007 at 1:09 PM
2
dorumi on 10/22/2007 at 1:18 PM
2
Inconvienent Lie on 06/16/2008 at 8:57 PM
1
If bacteria can excrete hydrocarbons, that is one more step towards getting rid of the Arab's strangelhold on our oil supply dependency.
Stop criticizing how this technology should work - according to your beliefs and get busy in your garage to create something better...
penywize55 on 06/20/2008 at 1:11 AM
1
vladlen on 06/26/2008 at 8:42 PM
1
Conventional concrete with pores and capillaries doesn't fit this purpose. Polymer concrete is denser, but is not bio-resistant. Only HEM concrete where pores and capillaries are filled with its own CSH gel non-permeable and bio-resistant. I use the same ingredients - cement, sand, water and high speed mixing. See www.hemconcrete.com.
Vladlen Fridman
vfrid38@comcast.net