These six men oversee more than $120 billion in research and technology investments in the United States.

JOHN LAMATTINA is the president of Pfizer Global Research and Development. Pfizer, headquartered in New York, NY, has the pharmaceutical industry's largest R&D budget -- $7.7 billion last year -- and one of the largest among all corporations. Trained as a chemist, LaMattina now oversees more than 12,500 scientists at eight major research campuses and other smaller facilities in five countries.

MICHAEL WYNNE is the acting undersecretary of defense for acquisition, technology, and logistics at the U.S. Department of Defense. He advises the secretary and deputy secretary of defense on acquisition, R&D, and advanced-technology matters. The military's budget for R&D and advanced-technology testing and evaluation for fiscal year 2005 is $69 billion.