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October 2001

The Proteomics Payoff

Now that the human genome project is done, proteins are set to displace genes as the new darlings of drug discovery. But are biologists up to the task?

By Jon Cohen

On June 26, 2000, President Bill Clinton and Prime Minister Tony Blair jointly announced that researchers had completed the first draft of the human genome, a map that spelled out the three billion letters of the genetic code. "Without a doubt, this is the most important, most wondrous map ever produced by humankind," said Clinton. Blair was equally effusive. "Let us be in no doubt about what we are witnessing today-a revolution in medical science whose implications far surpass even the discovery of antibiotics, the first great technological triumph of the 21st century," said Blair.

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